ISCI Overview and structure

Introduction

The International Stem Cell Initiative (ISCI) has conducted a series of projects to exploit the opportunities of large scale international co-operation between ES and iPS research groups to address issues of common interest in the biology of these cells:

ISCI1 (complete): 59 hEScell lines isolated in 17 laboratories in 11 countries were analyzed to characterise the surface antigen and gene expression signatures of the undifferentiated cells.

ISCI2 (complete): Focused on the defined media used for culturing hES cells and identifying the common genetic changes that occur to hES cells during prolonged in vitro culture. 

ISCI3 (in progress): The project aims to obtain a consensus about robust quantifiable techniques to assess the pluripotency of hES and hiPS cells. 

hES picture